I own a Logitech VX Revolution to accompany my Macbook Pro and it is easily the best, most comfortable mouse I've ever used. With every other mouse, I've had discomfort after using the mouse for long periods, but I've never experienced that with the VX. The contours on this thing is amazing.

Currently Logitech has a new flagship laptop mouse available, but I don't feel that it is as good as their previous generation.